NCT-506 产品活性：NCT-506 是一种口服生物可利用的醛脱氢酶 1A1 (ALDH1A1) 抑制剂，IC50 为 7 nM。 产品来源： https://www.medchemexpress.cn/NCT-506.html 研究领域：Metabolic Enzyme/Protease 作用靶点：Aldehyde Dehydrogenase (ALDH) In Vitro: NCT-506 inhibits ALDH1A1, hALDH1A3, hALDH2 with IC50s of 0.007±0.001, 16.4±3.99, and 21.5 μM, respectively. NCT-506 (100, 10, 1, 0.1 μM, 6 days) decreases significantly cell viability with an EC50 of 45.6 μM in OV-90 cells. NCT-506 inhibits MIA PaCa-2, OV-90, and HT-29 cells with IC50s of 0.077±0.040, 0.161±0.038, and 0.048±0.022 μM in aldefluor cell-based assays, respectively. NCT-506 is treated in combined with Paclitaxel, IC50s of 1202, 924, 870, 411, 102, and 31.8 nM with concentrations of NCT-506 at 0 (DMSO), 1, 3, 10, 20, 30 μM in SKOV-3-TR cells, respectively. 相关产品：Bioactive Compound Library Plus | Metabolism/Protease Compound Library | Anti-Cancer Compound Library | Glutamine Metabolism Compound Library | Anti-Cancer Metabolism Compound Library | Cancer Stem Cells Compound Library | Metabolic Enzyme Compound Library | Bioactive Compound Library Max | Disulfiram | 4-Hydroxynonenal | Alda-1 | Daidzin | α-NETA | 4-Diethylaminobenzaldehyde | Dyclonine hydrochloride | CVT-10216 | Win 18446 | NCT-501 | ALDH | IGUANA-1 | ALDH1A3-IN-3 | Prunetin | CM10 | NCT-505 | ALDH1A3-IN-1 | 3-Hydroxybenzaldehyde | CM037 | EN40 | KS106 | ALDH1A1-IN-2 | ALDH1A3-IN-2 | ALDH3A1-IN-1 | KS100 | FSI-TN42 | YG1702 | Nitrefazole | RV01 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。