耗材描述
Taprenepag isopropyl
产品活性:Taprenepag isopropyl 是一个具有高度选择性的 EP2 受体激动剂。
产品来源: https://www.medchemexpress.cn/Taprenepag_isopropyl.html
研究领域:GPCR/G Protein
作用靶点:Prostaglandin Receptor
In Vivo: Taprenepag isopropyl is a highly selective EP2 receptor agonist. Intraocular pressure (IOP) in the left, vehicle-dosed eye typically remains within the normal range. In the right (Taprenepag isopropyl-dosed) eye, IOP is reduced in all dose groups. In the high-dose group, IOP is reduced to the extent that it cannot be measured (<4mm Hg) on Days 22 and 29. There are no clinical signs or changes in body weight observed with any dose of Taprenepag isopropyl administration, and no
ocular findings occur for animals in the low-dose group (0.75 mg/day).
相关产品:Drug Repurposing Compound Library Plus | Clinical Compound Library Plus | Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Immunology/Inflammation Compound Library | Clinical Compound Library | Drug Repurposing Compound Library | Endocrinology Compound Library | Angiogenesis-Related Compound Library | Targeted Diversity Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Highly Selective Activators Library | Bioactive Compound Library Max | Prostaglandin E2 | EIPA | Prostaglandin E1 | Tranilast | U-46619 | PF-04418948 | Prostaglandin D2 | Dinoprost | Latanoprost | ONO-AE3-208 | Iloprost | Palupiprant | Selexipag | Treprostinil | L-798106 | Grapiprant | 16,16-Dimethyl prostaglandin E2 | DG-041 | Fevipiprant | GW627368 | Laropiprant | Asapiprant | L-161982 | AH 6809 | Ramatroban | RO1138452 | Cefminox sodium | Travoprost | Bimatoprost
品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物,我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物;10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域;设有专业的实验中心和严格的质控、验证体系;提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;产品的生物活性多经各国客户实验验证;Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;与世界各大制药公司及知名科研机构建立了长期的合作。