A-803467
面议
- 阿拉丁
- 生产商
- 国产
- 上海
- 现货
- 全国
- 2
- 1
分子式 C19H16ClNO4 分子量357.79 MDL号 MFCD10574689 属性 溶解性 DMSO 72 mg/mL Water <1 mg/mL Ethanol 11 mg/mL 存贮条件 储存温度-20°C //dec
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| 货号 | CAS号 | 操作 |
|---|---|---|
| A127941-50mg | 944261-79-4 | 询底价 |
| A127941-10mg | 944261-79-4 | 询底价 |
耗材描述
- 分子式 C19H16ClNO4
- 分子量357.79
- MDL号 MFCD10574689
属性
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | A-803467 |
| 备注 | A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM, blocks tetrodotoxin-resistant currents, exhibits >100-fold selectivity against human NaV1.2, NaV1.3, NaV1.5, and NaV1.7. |
| 生化机理 |
A 803467 is a selective Nav1.8 sodium channel blocker and analgesic. A 803467 blocks Nav1.8 with an IC50 of 8 nM and is over 100-fold more selective vs. human Nav1.2, 1.3, 1.5 and 1.7. A 803467 dose-dependently reduces behavioral responses in a variety of neuropathic and inflammatory pain models. |
| 别名 | 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide;5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide |
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