Lopinavir

面议

品牌：阿拉丁
厂商性质：生产商
产地类别：国产
产地：上海
货期：现货
服务地域：全国
规格：9
近期咨询：1

分子式 C37H48N4O5 分子量628.80 Beilstein号 EC号 MDL号 PubChem编号属性熔点 124-127 °C 溶解性 Soluble in DMF (~14 mg/ml), methanol, DMSO (

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上海阿拉丁生化科技股份有限公司

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配套的仪器设备？可以搭配的相关耗材试剂？

货号	CAS号	操作
L299096-10mg	192725-17-0	询底价
L299096-50mg	192725-17-0	询底价
L299096-1g	192725-17-0	询底价
L299096-250mg	192725-17-0	询底价
L129320-100mg	192725-17-0	询底价

耗材描述

分子式 C₃₇H₄₈N₄O₅
分子量628.80
Beilstein号
EC号
MDL号
PubChem编号

属性

熔点	124-127 °C
溶解性	Soluble in DMF (~14 mg/ml), methanol, DMSO (126 mg/ml at 25 °C), water (< 1 mg/ml at 25 °C), and ethanol (126 mg/ml at 25 °C).
存贮条件	储存温度 -20°C

描述

应用	Lopinavir has been used as a ZMPSTE24 and human immunodeficiency virus protease inhibitor.
产品介绍	Lopinavir is an antiviral HIV Protease Inhibitor. Lopinavir has insufficient bioavailability alone, so it is used in therapy in combination with Ritonavir, a HIV protease inhibitor, which inhibits cytochrome P450-3A4 (CYP3A4), a liver enzyme that normally metabolizes protease inhibitors. Lopinavir also has an ability to inhibit ZMPSTE24 (zinc metallopeptidase STE24).
生化机理	Lopinavir is an antiretroviral of the protease inhibitor class. Inhibition of HIV-1 protease prevents cleavage of the viral polyprotein precursor and results in the release of immature, noninfectious virions. A component of combination therapy to treat HIV/AIDS.
别名	ABT-378;洛匹那韦;洛吡那韦;(2S)-N-[(2R,4S,5S)-5-[[2-(2,6-二甲基苯氧基)乙酰]氨基]-4-羟基-1,6-二苯基-己-2-基]-3-甲基-2-(2-氧代-1,3-二氮杂环己-1-基)丁酰胺ABT-378;Aluviran;Koletra;ABT 378;ABT378;(2S)-N-[(2R,4S,5S)-5-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenyl-hexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide；(aS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-Pyrimidineacetamide;

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