化合物 T10036 T10036
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Product IntroductionBioactivity英文名: 10β,17β-dihydroxyestra-1,4-dien-3-one描述: 10β,17β-dihydroxyestra-1,4-dien-3-one is a b
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Product Introduction
Bioactivity
英文名: 10β,17β-dihydroxyestra-1,4-dien-3-one
描述: 10β,17β-dihydroxyestra-1,4-dien-3-one is a brain-targeting bioprecursor prodrug of the main human estrogen, 17β-estradiol. It alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain.
体内活性: 10β,17β-dihydroxyestra-1,4-dien-3-one (DHED), is converting to 17β-estradiol only in the brain. DHED as an E2-bioprecursor may be a viable approach for delivering E2 selectively into the brain for the potential treatment of hot flushes.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 250 mg/mL (866.91 mM)
关键字: 10beta,17beta-dihydroxyestra-1,4-dien-3-one | 10β,17β dihydroxyestra 1,4 dien 3 one | 10b,17b-dihydroxyestra-1,4-dien-3-one | 10β,17βdihydroxyestra1,4dien3one | 10β,17β-dihydroxyestra-1,4-dien-3-one
Bioactivity
英文名: 10β,17β-dihydroxyestra-1,4-dien-3-one
描述: 10β,17β-dihydroxyestra-1,4-dien-3-one is a brain-targeting bioprecursor prodrug of the main human estrogen, 17β-estradiol. It alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain.
体内活性: 10β,17β-dihydroxyestra-1,4-dien-3-one (DHED), is converting to 17β-estradiol only in the brain. DHED as an E2-bioprecursor may be a viable approach for delivering E2 selectively into the brain for the potential treatment of hot flushes.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 250 mg/mL (866.91 mM)
关键字: 10beta,17beta-dihydroxyestra-1,4-dien-3-one | 10β,17β dihydroxyestra 1,4 dien 3 one | 10b,17b-dihydroxyestra-1,4-dien-3-one | 10β,17βdihydroxyestra1,4dien3one | 10β,17β-dihydroxyestra-1,4-dien-3-one
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