Product IntroductionBioactivity英文名:
BF 227描述: BF 227 is a candidate for an amyloid imaging probe for PET (Ki: 4.3 nM for Aβ1-42 fibrils).
体外活性: BF-227 has a high binding affinity for Aβ1-42 fibrils. The Ki value for Aβ1-42 fibrils in competitive binding assay using [125I]BF-180 is 4.3 nM in BF-227 (Kd value of [125I]BF-180: 10.8 nM)[1]. The AUC for BF-227 (0.994) is much higher than that for FDG (0.839), indicating that BF-227 is more sensitive as well as more specific than FDG in diagnosing AD [2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字:
BF-227 |
BF 227 |
BF227