Product Introduction
Bioactivity


英文名: BRD 4354

描述: BRD 4354 是 HDAC5 和 HDAC9 的抑制剂，对 HDAC5 和 HDAC9 的 IC50 值分别为 0.85 和 1.88 μM。

体外活性: BRD 4354 在较高浓度下（3.88-13.8 μM）可抑制HDACs 4、6、7和8，但对其他一类HDACs 1、2、3的抑制作用较弱（IC50>40 μM）[1]。BRD 4354 对HDAC5和HDAC9具有中等的抑制能力，其半最大抑制浓度（IC50）分别为0.85 μM和1.88 μM。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 10 mg/mL (23.01 mM)


关键字: Histone deacetylases | inhibit | Inhibitor | HDAC | BRD4354 | BRD 4354 | BRD-4354

相关产品: BG45 | CDK/HDAC-IN-3 | Abexinostat | Quisinostat | CUDC-101 | NT160 | Valproic Acid | HDAC-IN-5 | M344 | BRD4097

相关库: Anti-Breast Cancer Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Epigenetics Compound Library | DNA Damage & Repair Compound Library | Anti-Pancreatic Cancer Compound Library | Reprogramming Compound Library | Histone Modification Compound Library | Bioactive Compound Library