化合物EACC T11142
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Product IntroductionBioactivity英文名: EACC描述: EACC 是自噬的可逆抑制剂，可阻断自噬通量。它对自噬体特异性的 SNARE Stx17 易位具有选择性抑制作用，从而阻止自噬体与溶酶体的融合。体外活性:
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Product Introduction
Bioactivity
英文名: EACC
描述: EACC 是自噬的可逆抑制剂，可阻断自噬通量。它对自噬体特异性的 SNARE Stx17 易位具有选择性抑制作用，从而阻止自噬体与溶酶体的融合。
体外活性: EACC inhibits autophagy by preventing SNARE Stx17 loading on autophagosomes. EACC does not affect RABs, tethers, and lysosomal SNARE but prevents their interaction with LC3 and Stx17.EACC blocks autophagosome-lysosome fusion but does not affect endo-lysosomal function.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 1mg/ml
关键字: Autophagy | Inhibitor | inhibit | EACC
相关产品: Daurisoline | DC661 | Oroxylin A | Zoledronic Acid | Rotenone | 4E1rcat | Heparin sodium salt | Rasagiline Mesylate | SU9516 | BIX-01294
相关库: Bioactive Compounds Library Max | Inhibitor Library | Autophagy Compound Library | Bioactive Compound Library
Bioactivity
英文名: EACC
描述: EACC 是自噬的可逆抑制剂，可阻断自噬通量。它对自噬体特异性的 SNARE Stx17 易位具有选择性抑制作用，从而阻止自噬体与溶酶体的融合。
体外活性: EACC inhibits autophagy by preventing SNARE Stx17 loading on autophagosomes. EACC does not affect RABs, tethers, and lysosomal SNARE but prevents their interaction with LC3 and Stx17.EACC blocks autophagosome-lysosome fusion but does not affect endo-lysosomal function.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 1mg/ml
关键字: Autophagy | Inhibitor | inhibit | EACC
相关产品: Daurisoline | DC661 | Oroxylin A | Zoledronic Acid | Rotenone | 4E1rcat | Heparin sodium salt | Rasagiline Mesylate | SU9516 | BIX-01294
相关库: Bioactive Compounds Library Max | Inhibitor Library | Autophagy Compound Library | Bioactive Compound Library
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