化合物Elubrixin T11179
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Product IntroductionBioactivity英文名: Elubrixin描述: Elubrixin (SB-656933) 是一种有效和特异性的 CXCR2 和 IL-8 受体拮抗剂。 Elubrixin 可用于炎症性疾病的
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Product Introduction
Bioactivity
英文名: Elubrixin
描述: Elubrixin (SB-656933) 是一种有效和特异性的 CXCR2 和 IL-8 受体拮抗剂。 Elubrixin 可用于炎症性疾病的研究，例如炎症性肠病和气道炎症。
体外活性: Elubrixin inhibits neutrophil CD11b upregulation with an IC50 of 260.7 nM and shapes change with an IC50 of 310.5 nM. Elubrixin has an inhibitory effect on neutrophils in a dose-dependent manner[3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 10 mg/mL (21.58 mM)
关键字: airway | Inhibitor | inhibit | Interleukin Related | CXCR | IL-8 | CXC chemokine receptors | neutrophil-mediated | CXCR2 | Elubrixin | anti-inflammatory | SB656933 | CD11b | bowel | SB 656933
相关产品: Broussonin A | Mitraphylline | Hirsutenone | Dexamethasone | Kaempferol 3-O-β-D-glucuronide | Isotetrandrine | Astringin | BIRT-377 | Jolkinolide B | Desoxo-narchinol A
相关库: Drug Repurposing Compound Library | Pyroptosis Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | GPCR Compound Library | Inhibitor Library | Anti-Cancer Clinical Compound Library
Bioactivity
英文名: Elubrixin
描述: Elubrixin (SB-656933) 是一种有效和特异性的 CXCR2 和 IL-8 受体拮抗剂。 Elubrixin 可用于炎症性疾病的研究，例如炎症性肠病和气道炎症。
体外活性: Elubrixin inhibits neutrophil CD11b upregulation with an IC50 of 260.7 nM and shapes change with an IC50 of 310.5 nM. Elubrixin has an inhibitory effect on neutrophils in a dose-dependent manner[3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 10 mg/mL (21.58 mM)
关键字: airway | Inhibitor | inhibit | Interleukin Related | CXCR | IL-8 | CXC chemokine receptors | neutrophil-mediated | CXCR2 | Elubrixin | anti-inflammatory | SB656933 | CD11b | bowel | SB 656933
相关产品: Broussonin A | Mitraphylline | Hirsutenone | Dexamethasone | Kaempferol 3-O-β-D-glucuronide | Isotetrandrine | Astringin | BIRT-377 | Jolkinolide B | Desoxo-narchinol A
相关库: Drug Repurposing Compound Library | Pyroptosis Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | GPCR Compound Library | Inhibitor Library | Anti-Cancer Clinical Compound Library
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