Product Introduction
Bioactivity


英文名: Beclometasone dipropionate

描述: Beclometasone dipropionate (Vancenase) 是具有口服活性的糖皮质激素，具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物，Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。

体外活性: Beclometasone dipropionate （BDP）是用于治疗哮喘和过敏性鼻炎（AR）的抗炎皮质类固醇。BDP曾经开发为治疗AR的水性鼻用制剂。此外，BDP也曾以氯氟烃（CFC）计量剂量吸入器鼻喷雾的形式推出干鼻气雾制剂，但含CFC的制剂已经从市场撤回，目前已不再提供。BDP氢氟烃（HFA）吸入气雾剂目前可供患者使用，适用于5岁及以上患者哮喘的维持治疗和预防治疗。新近研发的BDP HFA鼻用气雾剂，是一种治疗AR的鼻内气雾制剂。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (105.56 mM)
Ethanol : 18 mg/mL (34.55 mM)


关键字: Beclomethasone Dipropionate | Beclometasone dipropionate | iNOS | 16HBE cells | STAT-1 | Beclometasone Dipropionate | Beclomethasone | Inhibitor | Beclometasone | inhibit | Glucocorticoid Receptor | asthma | inflammation

相关产品: GSK9027 | Finerenone | Cort108297 | Glucagon (1-29), bovine, human, porcine hydrochloride | Corticosterone | Methylprednisolone succinate | Ecdysone | Cortisone | Betamethasone valerate | TPI-1

相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | ReFRAME Related Library | FDA-Approved & Pharmacopeia Drug Library | Anti-Cancer Drug Library | Anti-Cancer Clinical Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | NO PAINS Compound Library | Bioactive Compound Library