Product Introduction
Bioactivity


英文名: IFN alpha-IFNAR-IN-1 hydrochloride

描述: IFN alpha-IFNAR-IN-1 hydrochloride 是 IFN-α 和 IFNAR 相互作用的抑制剂。 IFN alpha-IFNAR-IN-1 hydrochloride 抑制 BM-pDCs 的 MVA 诱导的 IFN-α 反应，IC50 为 2-8 μM。

体外活性: IFN alpha-IFNAR-IN-1 hydrochloride 在经CpG2216处理、poly(I:C)刺激和VSV-M2感染后抑制了IFN-α的反应，而在这些条件下，总IL-12的产生受到的影响相对较小。IFN alpha-IFNAR-IN-1 hydrochloride特异性地抑制了BM-pDCs诱导的IFN-α反应。IFN alpha-IFNAR-IN-1 hydrochloride通过直接与IFN-α[1]交互从而发挥免疫抑制活性。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : 16 mg/mL (50.66 mM)
DMSO : 95 mg/mL (300.77 mM)


关键字: IFN alpha-IFNAR-IN-1 Hydrochloride | IFN α-IFNAR-IN-1 Hydrochloride | Inhibitor | Interferon-α/β receptor | Interferon-alpha/beta receptor | IFN a-IFNAR-IN-1 Hydrochloride | inhibit | IFN alpha IFNAR IN 1 hydrochloride | IFNAR | IFN alphaIFNARIN1 hydrochloride

相关产品: Anti-Mouse IFN gamma Antibody (H22) | Anifrolumab | Delmitide acetate | Anti-Mouse IFNAR1 Antibody (MAR1-5A3) | Deucravacitinib | Ginsenoside F3 | AX-024 hydrochloride | CCCP | Vadimezan | Interferon receptor inducer-1

相关库: Bioactive Compounds Library Max | Inhibitor Library | PPI Inhibitor Library | Bioactive Compound Library