Product Introduction
Bioactivity


英文名: IR415

描述: IR415 选择性地与 HBx 相互作用 (Kd=2 nM) 并阻断 HBV 介导的 RNAi 抑制，逆转 HBx 蛋白对 Dicer 核糖核酸内切酶活性的抑制作用。IR415 具有抗 HBV 的活性。

体外活性: IR415 (50-200 μM) has a dose-dependent inhibitory effect on HBx, with a minimal effective concentration of 50 μM in HepG2/GFP-shRNA line transfected with HBx.Hepatitis B virus X protein (HBx) as a suppressor of host defenses consisting of RNAi-based silencing of viral genes.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 125 mg/mL (421.81 mM)


关键字: Inhibitor | inhibit | cell | HepG2 | HBX | IR 415 | IR-415 | replication | virus | Hepatitis B virus | HBV | VSR | IR415 | hepatitis B

相关产品: Tobevibart | Yhhu6669 | Niranthin | Coclauril | Thiamine hydrochloride | Tenofovir Disoproxil Fumarate | HBV-IN-40 | Osthole | Morphothiadin | Telbivudine

相关库: Bioactive Compounds Library Max | Inhibitor Library | Anti-Viral Compound Library | Bioactive Compound Library