Product Introduction
Bioactivity


英文名: N-Desmethyl-Apalutamide

描述: N-Desmethyl-Apalutamide 是一种 Apalutamide 的活性代谢产物，主要由 CYP2C8 和 CYP3A4 介导形成。它是一种低活性的雄激素受体拮抗剂，其作用力是 Apalutamide 活性的三分之一。它是中等至强的CYP3A4和CYP2B6诱导剂，并具有优异的血浆蛋白结合浓度。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (107.9 mM)


关键字: CYP3A4 | plasma-proteins | Inhibitor | inhibit | Metabolite | Cytochrome P450 | N Desmethyl Apalutamide | pharmacological | CYP2B6 | NDesmethylApalutamide | CYPs | Androgen Receptor | CYP2C8 | N-Desmethyl-Apalutamide

相关产品: Fenofibrate | Glycycoumarin | Zederone | 1-Ethynylnaphthalene | Bucolome | YM 511 | CYP4A11/CYP4F2-IN-2 | Apigenin | K777 | Saponarin

相关库: Anti-Prostate Cancer Compound Library | Transcription Factor-Targeted Compound Library | Anti-Cancer Compound Library | Anti-Metabolism Disease Compound Library | Inhibitor Library | Nuclear Receptor Compound Library | Endocrinology-Hormone Compound Library | Metabolism Compound Library | NO PAINS Compound Library | Bioactive Compound Library