Product Introduction
Bioactivity


英文名: SPD304 dihydrochloride

描述: SPD304 dihydrochloride 是 TNF-α 的特异性抑制剂，IC50 为 22 µM。 SPD304 dihydrochloride 促进 TNF 三聚体的解离。

体外活性: The survivability of aHSCs is significantly rescued by SPD304 dihydrochloride (2 μM). The production of lipid hydroxides and intracellular GSH are increased as well. GA (75 μM) and SPD304 dihydrochloride (2 μM) downregulate TRADD (almost 2-fold) and p−RIP3 (1.4−fold) compared to GA and promote the activation of caspase 8[4].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 6.2 mg/mL (10 mM)


关键字: SPD304 Dihydrochloride | SPD304 | SPD-304 Dihydrochloride | SPD-304 | SPD 304 Dihydrochloride | SPD 304 | SPD304 dihydrochloride | SPD-304 dihydrochloride

相关产品: EJMC-1 | Mussaenoside | Neochlorogenic acid | Acetylcysteine | Zederone | RIPK-IN-4 | Amrinone | Nepetoidin B | Anti-inflammatory agent 42 | Heliangin

相关库: NF-κB Signaling Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Bioactive Compound Library