化合物 T12996 T12996
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Product IntroductionBioactivity英文名: Squalamine lactate描述: Squalamine lactate is an aminosterol compound discovered in the
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Product Introduction
Bioactivity
英文名: Squalamine lactate
描述: Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.
体外活性: Squalamine lactate has a more general effect on the cell signaling cascade, which is common to VEGF and other growth factors[1]. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin[2].
体内活性: When administered intravitreally and therefore requires intravenous dosing, Squalamine is ineffective . However, systemic dosing has yielded promising results in rats as well as humans[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 36.66 mg/mL (51.06 mM)
关键字: Squalamine lactate | Squalamine Lactate
Bioactivity
英文名: Squalamine lactate
描述: Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.
体外活性: Squalamine lactate has a more general effect on the cell signaling cascade, which is common to VEGF and other growth factors[1]. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin[2].
体内活性: When administered intravitreally and therefore requires intravenous dosing, Squalamine is ineffective . However, systemic dosing has yielded promising results in rats as well as humans[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 36.66 mg/mL (51.06 mM)
关键字: Squalamine lactate | Squalamine Lactate
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