Product Introduction
Bioactivity


英文名: Asoxime dichloride

描述: Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) 是乙酰胆碱受体 (AChRs) 拮抗剂，包括烟碱受体，α7 乙酰胆碱受体。Asoxime dichloride 参与调节免疫应答。Asoxime dichloride 可作为抗原使用，改善神经系统的免疫效果。

体内活性: HI-6与钥孔鳍螺血蓝蛋白(KLH)的组合能产生与Freund's complete adjuvant[1]几乎同等效力的疫苗。Asoxime dichloride（肌肉注射于后肢；中位致死剂量的2%和0.2%，即15.6和1.56 mg/kg；21或65天）当KLH为1 mg/kg时，能够以剂量依赖的方式显著提高疫苗的效力[1]。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : 10 mg/mL (27.8 mM)


关键字: HI6 | HI 6 | Asoxime | Asoxime Dichloride

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相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | ReFRAME Related Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Inhibitor Library | Bioactive Compound Library