化合物 T14570 T14570
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Product IntroductionBioactivity英文名: BI 99179描述: BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibi
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Product Introduction
Bioactivity
英文名: BI 99179
描述: BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1].
体外活性: BI 99179 is potent in the mouse hypothalamic N-42 cell with an IC50 of 0.6 μM and it shows no significant LDH release in the cytotoxicity assay up to 30 μM[1].
体内活性: BI 99179 has a super pharmacokinetic profile in male Han/Wistar rats (oral application of 4 mg/kg)with half life (t1/2) of 3.0 h[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: BI 99179 | BI-99179
相关产品: FASN-IN-1 | Fas C-Terminal Tripeptide Acetate | FASN-IN-3 | GSK2194069 | TVB-3166 | Pyrazinamide | Isoscoparin | Fatostatin hydrobromide | Pedunculoside | Betulin
Bioactivity
英文名: BI 99179
描述: BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1].
体外活性: BI 99179 is potent in the mouse hypothalamic N-42 cell with an IC50 of 0.6 μM and it shows no significant LDH release in the cytotoxicity assay up to 30 μM[1].
体内活性: BI 99179 has a super pharmacokinetic profile in male Han/Wistar rats (oral application of 4 mg/kg)with half life (t1/2) of 3.0 h[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: BI 99179 | BI-99179
相关产品: FASN-IN-1 | Fas C-Terminal Tripeptide Acetate | FASN-IN-3 | GSK2194069 | TVB-3166 | Pyrazinamide | Isoscoparin | Fatostatin hydrobromide | Pedunculoside | Betulin
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