Product Introduction
Bioactivity


英文名: Liothyronine

描述: Liothyronine (Tresitope) 是一种有效的甲状腺激素，能够激活 β1 甲状腺激素受体 (TRβ1)。

体外活性: Triiodothyronine (0.01-0.1 μM) results in a decrease in the TRalpha1:TRalpha2 mRNA ratio in HepG2 cells. High liothyronine levels induces a low TRalpha1:TRalpha2 ratio which can protect the cell from excessive triiodothyronine-induced gene expression[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: 5% DMSO+95% Saline : 4.55 mg/mL (6.99 mM, suspension)
DMSO : 1mg/ml


关键字: Inhibitor | Endogenous Metabolite | Liothyronine | Thyroid Hormone Receptor | inhibit | TRα | T-3 | T 3 | thyroid hormone | THR | TRβ

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相关库: Human Endogenous Metabolite Library | Drug Repurposing Compound Library | Approved Drug Library | ReFRAME Related Library | Drug-induced Liver Injury (DILI) Compound Library | Human Metabolite Library | Natural Product Library for HTS | Endocrinology-Hormone Compound Library | NO PAINS Compound Library | Bioactive Compound Library