Product Introduction
Bioactivity


英文名: Amfenac Sodium Hydrate

描述: Amfenac Sodium Hydrate 是一种含有乙酸部分的非甾体镇痛抗炎药，是 COX-2抑制剂。

体外活性: 在体内,Amfenac局部给药或口服给药于动物时,产生的刺激性小,治疗效率高.Amfenac作用于体内具有的特性. Amfenac（4 mg/kg）能够抑制急性和慢性炎症,具有解热镇痛的功能.

体内活性: Amfenac能够显著抑制COX-1（IC50=0.25 μM）和COX-2（IC50=0.15 μM）。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 4 mg/mL (13.54 mM)
H2O : 54 mg/mL (182.9 mM)
DMSO : 3.85 mg/mL (13.03 mM)


关键字: Amfenac Sodium Hydrate | Amfenac Sodium | Cyclooxygenase | COX | Inhibitor | inhibit

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