Product Introduction
Bioactivity


英文名: Thalidomide-O-amido-C6-NH2 hydrochloride

描述: Thalidomide-O-amido-C6-NH2 hydrochloride 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物，。它可用于 PROTAC 分子的合成。

体外活性: PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: ThalidomideOamidoC6NH2 hydrochloride | Inhibitor | inhibit | Thalidomide-O-amido-C6-NH2 Hydrochloride | E3 Ligase Ligand-Linker Conjugates | Thalidomide-O-amido-C-6-NH2 hydrochloride | Thalidomide O amido C6 NH2 hydrochloride

相关产品: Thalidomide-NH-C6-NH2 hydrochloride | Thalidomide-O-amido-C3-NH2 TFA | Thalidomide-O-C4-NH2 hydrochloride | Thalidomide-O-C6-NH2 hydrochloride | Thalidomide-O-amido-C4-NH2 TFA | (S,R,S)-AHPC-PEG3-N3 | Thalidomide 4'-ether-alkylC2-amine hydrochloride | Thalidomide-O-amido-PEG3-C2-NH2 TFA | Thalidomide-NH-C4-NH-Boc | Pomalidomide-PEG4-C-COOH