Product Introduction
Bioactivity


英文名: Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride

描述: Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand derived from Thalidomide and a 3-unit PEG linker. It is specifically designed for use in PROTAC technology, which utilizes small molecules to induce protein degradation [1].

体外活性: Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is composed of Degron (E3 ubiquitin ligase) and a linker, and they are used in PROTAC technology. Thalidomide-O-amido-PEG3-C2-NH2 binds to the targeting ligand to induce the target protein (including BRD4, BRD2, and BRD3) degradation[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Thalidomide-O-amido-PEG3-C2-NH2 Hydrochloride | Thalidomide O amido PEG3 C2 NH2 hydrochloride | ThalidomideOamidoPEG3C2NH2 hydrochloride | Thalidomide-O-amido-PEG-3-C2-NH2 hydrochloride