S-亚硝基谷胱甘肽 T19930
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Product IntroductionBioactivity英文名: Nitrosoglutathione描述: Nitrosoglutathione (GSNO) 是一种外源性的 NO 供体，是大鼠酒精脱氢酶III 类同工酶的底物，能够减
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Product Introduction
Bioactivity
英文名: Nitrosoglutathione
描述: Nitrosoglutathione (GSNO) 是一种外源性的 NO 供体，是大鼠酒精脱氢酶III 类同工酶的底物，能够减少脑血管紧张素II 依赖性及非依赖型的 AT1 受体反应。
体外活性: GSNO completely abolished the AngII-dependent AT1 receptor-mediated vasoconstriction of cerebral arteries. GSNO had no impact on responses to other vasoconstrictors sharing (phenylephrine, U46619) or not (5-HT) the same signalling pathway[1].
体内活性: Elevated blood pressure, proteinuria, and intrauterine growth restriction associated with PE were induced in Sprague-Dawley rats using L-NAME. These were partially reversed with the use of GSNO[3].
存储条件: store at low temperature,keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : Soluble
H2O : 20 mg/ml(59.47 mM)
关键字: I/R | RVC 588 | Nitrosoglutathione | inhibit | antioxidant | Inhibitor | RVC-588 | Angiotensin Receptor | injury | superoxide | ischemia | RVC588
相关产品: Olodanrigan | L162389 | Azilsartan | Ramipril | N-Acetyl-Ser-Asp-Lys-Pro | Trans-Tranilast | Enalaprilat Dihydrate | Vicenin 2 | Moexipril hydrochloride | L-162,313
相关库: ReFRAME Related Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Endocrinology-Hormone Compound Library | Bioactive Compound Library
Bioactivity
英文名: Nitrosoglutathione
描述: Nitrosoglutathione (GSNO) 是一种外源性的 NO 供体，是大鼠酒精脱氢酶III 类同工酶的底物，能够减少脑血管紧张素II 依赖性及非依赖型的 AT1 受体反应。
体外活性: GSNO completely abolished the AngII-dependent AT1 receptor-mediated vasoconstriction of cerebral arteries. GSNO had no impact on responses to other vasoconstrictors sharing (phenylephrine, U46619) or not (5-HT) the same signalling pathway[1].
体内活性: Elevated blood pressure, proteinuria, and intrauterine growth restriction associated with PE were induced in Sprague-Dawley rats using L-NAME. These were partially reversed with the use of GSNO[3].
存储条件: store at low temperature,keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : Soluble
H2O : 20 mg/ml(59.47 mM)
关键字: I/R | RVC 588 | Nitrosoglutathione | inhibit | antioxidant | Inhibitor | RVC-588 | Angiotensin Receptor | injury | superoxide | ischemia | RVC588
相关产品: Olodanrigan | L162389 | Azilsartan | Ramipril | N-Acetyl-Ser-Asp-Lys-Pro | Trans-Tranilast | Enalaprilat Dihydrate | Vicenin 2 | Moexipril hydrochloride | L-162,313
相关库: ReFRAME Related Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Endocrinology-Hormone Compound Library | Bioactive Compound Library
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