Product Introduction
Bioactivity


英文名: SEW​2871

描述: SEW 2871 是一种可口服的高选择性 S1P1激动剂，EC50为 13.8 nM。它减少血液中的淋巴细胞数量，可用于糖尿病、阿尔茨海默氏病、肝纤维化和炎症相关研究。它激活 ERK、Akt 和 Rac 信号通路，并诱导 S1P1 内在化和再循环。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 8.8 mg/mL(20 mM)


关键字: SEW​2871 | Alzheimer’s disease | Crohn's disease | Lysophospholipid Receptor | Akt | SEW?2871 | Protein kinase B | LPL Receptor | orally active | PKB | diabetes | inhibit | colitis | Extracellular signal regulated kinases | SEW-2871 | ischaemia-reperfusion injury | SEW 2871 | liver fibrosis | ERK | LX-2 cells | Inhibitor

相关产品: Amiselimod hydrochloride | CYM50308 | BMS-960 | PF-543 | JTE-013 | S1p receptor agonist 1 | GLPG2938 | GSK2018682 | Fingolimod hydrochloride | PF429242 dihydrochloride

相关库: Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Obesity Compound Library | Orally Active Compound Library | Bioactive Compound Library