Product Introduction
Bioactivity


英文名: Epidermal Growth Factor Receptor Peptide Acetate

描述: Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate (96249-43-3 Free base)) 存在于细胞表面，通过与其特异性配体的结合而被激活。EGFR 属于受体酪氨酸激酶(RTK) 的 ErbB 家族。

体外活性: This autophosphorylation elicits downstream activation and signaling by several other proteins that associate with the phosphorylated tyrosines through their own phosphotyrosine-binding SH2 domains.?These downstream signaling proteins initiate several signal transduction cascades, principally the MAPK, Akt and JNK pathways, which lead to DNA synthesis and cell proliferation.Such proteins modulate phenotypes such as cell migration, adhesion, and proliferation.?Activation of the receptor is important for the innate immune response in human skin.?

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : 10 mg/mL (7.27mM)
DMSO : 133mg/mL(96.62mM)


关键字: Epidermal Growth Factor Receptor Peptide Acetate

相关库: Anti-Breast Cancer Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Anti-Ovarian Cancer Compound Library | Peptide Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Active Compound Library | NO PAINS Compound Library