Product Introduction
Bioactivity


英文名: CID 5951923

描述: CID 5951923 是 KLF5 转录因子的抑制剂，IC50 为 603 nM。

体外活性: CID 5951923 (10 μM) inhibits the proliferation of cancer cell lines mainly in highly expressing KLF5 cells. CID 5951923 (0.001, 0.01, 0.1, 1, 10, 100 μM) inhibits proliferation of DLD-1 cells in a dose-dependent manner. CID 5951923 (10 μM) significantly decreases endogenous KLF5 levels in the DLD-1 cells, downregulates EGR1, and increases phosphorylation levels of pEGFFpY1068[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 3.82 mg/mL (10 mM)


关键字: Krüppel-like factor | CID5951923 | KLF5 | inhibit | cancer | factor | KLF | CID-5951923 | CID 5951923 | transcription | Inhibitor | Krüppel-like

相关产品: BMH-21 | Chebulinic acid | UNC9512 | Zoliflodacin | Pemetrexed | Enrofloxacin | Tetrapeptide | Oxolinic acid | L67 | AT-130

相关库: Transcription Factor-Targeted Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | DNA Damage & Repair Compound Library | Bioactive Compound Library