Co 101244盐酸盐 T22674
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Product IntroductionBioactivity英文名: Co 101244 hydrochloride描述: Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphe
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Product Introduction
Bioactivity
英文名: Co 101244 hydrochloride
描述: Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) 是一种含有 NR2B 的 NMDA 受体拮抗剂。
体外活性: Co 101244 enhances neuroprotection and reduces NMDA-evoked Ca2+?elevations effectively [1].
体内活性: Administration of 1 mg/kg s.c. Co 101244 displayed antidyskinetic effects with the reduction of 67% while sparing levodopa motor benefit[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : < 35 mg/mL (92.62mM)
DMSO : < 17.5 mg/mL (46.31mM)
关键字: Inhibitor | Co 101244 | Co-101244 | Co 101244 hydrochloride | Co 101244 Hydrochloride | Ionotropic glutamate receptors | inhibit | NR2B | Co101244 | PD174494 | iGluR | PD 174494 | neuroprotective | PD-174494 | NMDA
相关产品: Mephenesin | Perzinfotel | UBP710 | CGP 78608 hydrochloride | (-)-Dizocilpine maleate | Traxoprodil | Radiprodil | Transtorine | D-AP5 | Kynurenic acid
相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Anti-Parkinson's Disease Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Antidepressant Compound Library | Inhibitor Library | Anti-Alzheimer's Disease Compound Library | Bioactive Compound Library
Bioactivity
英文名: Co 101244 hydrochloride
描述: Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) 是一种含有 NR2B 的 NMDA 受体拮抗剂。
体外活性: Co 101244 enhances neuroprotection and reduces NMDA-evoked Ca2+?elevations effectively [1].
体内活性: Administration of 1 mg/kg s.c. Co 101244 displayed antidyskinetic effects with the reduction of 67% while sparing levodopa motor benefit[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : < 35 mg/mL (92.62mM)
DMSO : < 17.5 mg/mL (46.31mM)
关键字: Inhibitor | Co 101244 | Co-101244 | Co 101244 hydrochloride | Co 101244 Hydrochloride | Ionotropic glutamate receptors | inhibit | NR2B | Co101244 | PD174494 | iGluR | PD 174494 | neuroprotective | PD-174494 | NMDA
相关产品: Mephenesin | Perzinfotel | UBP710 | CGP 78608 hydrochloride | (-)-Dizocilpine maleate | Traxoprodil | Radiprodil | Transtorine | D-AP5 | Kynurenic acid
相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Anti-Parkinson's Disease Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Antidepressant Compound Library | Inhibitor Library | Anti-Alzheimer's Disease Compound Library | Bioactive Compound Library
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