Product Introduction
Bioactivity


英文名: Aloin

描述: Aloin (Aloin-A) 是天然的抗肿瘤蒽醌苷，具有铁螯合特性。

体内活性: 在MCF-7细胞系中,Aloin通过诱导细胞凋亡引起处于有丝分裂期的细胞比率减少,抑制拓扑IIα蛋白表达,并下调细胞周期B1蛋白的表达。HeLaS3细胞中,Aloin在生理浓度(IC50=97 μM)下表现出明显的抗增殖作用,导致细胞周期阻滞在S期,明显增加细胞凋亡。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 2 mg/mL (4.78 mM)
H2O : 1 mg/mL (2.39 mM)
DMSO : 4.18 mg/mL (10 mM)


关键字: Aloin | inhibit | Inhibitor

相关产品: Wilforlide A | 2-Ketoglutaric acid | Glyasperin C | Swertiajaponin | AC1NS4RE | Temocapil | SU5214 | Methyl cinnamate | Retusin | 2-Methoxycinnamic acid

相关库: Drug Repurposing Compound Library | Anti-Cancer Drug Library | Bioactive Compounds Library Max | Saccharide and Glycoside Natural Product Library | Anti-Metabolism Disease Compound Library | Inhibitor Library | Traditional Chinese Medicine Monomer Library | Anti-Cancer Approved Drug Library | Anti-Cancer Active Compound Library | Protease Inhibitor Library