Product Introduction
Bioactivity


英文名: 1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)

描述: 1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol . 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM. It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS. It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Methanol : Sparingly Soluble


关键字: 1Arachidonoyl Lysophosphatidic Acid (ammonium salt) | 1-Arachidonoyl Lysophosphatidic Acid | 1 Arachidonoyl Lysophosphatidic Acid (ammonium salt)