CAY10486 T36549
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Product IntroductionBioactivity英文名: CAY10486描述: Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2)
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Product Introduction
Bioactivity
英文名: CAY10486
描述: Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Ethanol : 20 mg/mL
DMSO:PBS (pH 7.2)(1:5) : 0.5 mg/mL
DMSO : 30 mg/mL
DMF : 30 mg/mL
关键字: CAY 10486 | CAY10486 | CAY-10486
Bioactivity
英文名: CAY10486
描述: Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Ethanol : 20 mg/mL
DMSO:PBS (pH 7.2)(1:5) : 0.5 mg/mL
DMSO : 30 mg/mL
DMF : 30 mg/mL
关键字: CAY 10486 | CAY10486 | CAY-10486
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