化合物 C108 T38387
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Product IntroductionBioactivity英文名: Compound C108描述: Compound C108 是 GTPase 激活蛋白 SH3 结构域结合蛋白 2 (G3BP2) 的抑制剂。 Compound C10
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Product Introduction
Bioactivity
英文名: Compound C108
描述: Compound C108 是 GTPase 激活蛋白 SH3 结构域结合蛋白 2 (G3BP2) 的抑制剂。 Compound C108可用于乳腺肿瘤和食管鳞状细胞癌的研究。
体外活性: In BT474 cells, Compound C108 (1 μM) shows anti-tumor activity[1]. In G3BP2 overexpressing KYSE410 cells and LINC01554 transfected KYSE30 cells, Compound C108 (4 μM) reduces the protein expression of G3BP2 and attenuates ESCC cell metastasis, migration and invasion[2].
体内活性: In a mouse xenograft model of breast cancer, compound C108 (1 μM) reduces the proportion of tumor-initiating cells approximately 10-fold[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMF:PBS(pH 7.2)(1:6) : 0.14 mg/mL
DMF : 1 mg/mL
DMSO : 22.5 mg/mL (83.2 mM)
关键字: Compound C-108 | Compound C 108 | Compound C108
相关产品: Tyrphostin 8 | Gancaonin I | Exo-1 | RBC8 | CCG-63802 | IMM-01 | QS11 | Dynamin inhibitory peptide Acetate | ML-097 | CCG 203769
相关库: Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Inhibitor Library | Bioactive Compound Library
Bioactivity
英文名: Compound C108
描述: Compound C108 是 GTPase 激活蛋白 SH3 结构域结合蛋白 2 (G3BP2) 的抑制剂。 Compound C108可用于乳腺肿瘤和食管鳞状细胞癌的研究。
体外活性: In BT474 cells, Compound C108 (1 μM) shows anti-tumor activity[1]. In G3BP2 overexpressing KYSE410 cells and LINC01554 transfected KYSE30 cells, Compound C108 (4 μM) reduces the protein expression of G3BP2 and attenuates ESCC cell metastasis, migration and invasion[2].
体内活性: In a mouse xenograft model of breast cancer, compound C108 (1 μM) reduces the proportion of tumor-initiating cells approximately 10-fold[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMF:PBS(pH 7.2)(1:6) : 0.14 mg/mL
DMF : 1 mg/mL
DMSO : 22.5 mg/mL (83.2 mM)
关键字: Compound C-108 | Compound C 108 | Compound C108
相关产品: Tyrphostin 8 | Gancaonin I | Exo-1 | RBC8 | CCG-63802 | IMM-01 | QS11 | Dynamin inhibitory peptide Acetate | ML-097 | CCG 203769
相关库: Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Inhibitor Library | Bioactive Compound Library
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