Ipatasertib-NH2 dihydrochloride T38393
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Product IntroductionBioactivity英文名: Ipatasertib-NH2 dihydrochloride描述: Ipatasertib-NH2 dihydrochloride is a ligand for th
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Product Introduction
Bioactivity
英文名: Ipatasertib-NH2 dihydrochloride
描述: Ipatasertib-NH2 dihydrochloride is a ligand for the target protein AKT in PROTAC INY-03-041. INY-03-041 consists of Ipatasertib-NH2, a ten-hydrocarbon linker, and the CRBN ligand Lenalidomide, which acts as an E3 ubiquitin ligase.
体外活性: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: IpatasertibNH2 dihydrochloride | RG7440-NH2 | GDC-0068-NH2 Dihydrochloride | GDC-0068-NH2 | Ipatasertib NH2 dihydrochloride | Ipatasertib-NH2 | Ipatasertib-NH-2 dihydrochloride | RG7440-NH2 Dihydrochloride | Ipatasertib-NH2 Dihydrochloride
Bioactivity
英文名: Ipatasertib-NH2 dihydrochloride
描述: Ipatasertib-NH2 dihydrochloride is a ligand for the target protein AKT in PROTAC INY-03-041. INY-03-041 consists of Ipatasertib-NH2, a ten-hydrocarbon linker, and the CRBN ligand Lenalidomide, which acts as an E3 ubiquitin ligase.
体外活性: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: IpatasertibNH2 dihydrochloride | RG7440-NH2 | GDC-0068-NH2 Dihydrochloride | GDC-0068-NH2 | Ipatasertib NH2 dihydrochloride | Ipatasertib-NH2 | Ipatasertib-NH-2 dihydrochloride | RG7440-NH2 Dihydrochloride | Ipatasertib-NH2 Dihydrochloride
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