Product Introduction
Bioactivity


英文名: CASIN

描述: CASIN (Pirl1-related Compound 2) 是选择性GTPase Cdc42抑制剂，IC50值是 2 uM。

体外活性: CASIN (5 uM) could reduce the elevated level of active Cdc42 in aged primitive hematopoietic cells to the level in young cells.

体内活性: CASIN can reverse the aging-related and polarity phenotype of aged HSCs to that of young HSCs.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (179.5 mM)


关键字: Ras | multiple myeloma | drug resistance | inhibit | Apoptosis | Inhibitor | bortezomib | CASIN

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