Product Introduction
Bioactivity


英文名: Oxaceprol

描述: Oxaceprol (N-Acetyl-L-hydroxyproline) 是一种可口服的、具有显著抗炎作用的 L-脯氨酸衍生物，常用于研究骨关节炎和类风湿性关节炎。

体内活性: Oxaceprol, an established therapeutic agent for osteoarthritis, had no effect on macrophage prostaglandin E2 release in vitro and inhibited carrageenan paw oedema at high doses (18-150 mg/kg p.o.).?In the same dose range, oxaceprol was comparable to indomethacin (3 mg/kg p.o.) as an inhibitor of yeast hyperalgaesia and at 6-50 mg/kg/day p.o. had a mild, variable inhibitory effect on cotton pellet granuloma formation[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 100 mg/mL (577.47 mM)


关键字: Oxaceprol | osteoarthritis | inhibit | arthritis | anti-inflammatory | rheumatoid | Inhibitor | antirheumatic

相关库: ReFRAME Related Library | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compounds Library Max | Orally Active Compound Library | RO5 Drug-like Natural Product Library | NO PAINS Compound Library | Natural Product Library | Bioactive Compound Library