Product Introduction
Bioactivity


英文名: C-176

描述: C-176 (STING inhibitor 1) 是干扰素基因刺激受体的一种强效共价抑制剂。

体外活性: C-176 significantly reduces STING-mediated, but not RIG-I- or TBK1-mediated, IFNβ reporter activity. Pretreatment with C-176 markedly reduces the CMA-mediated induction of serum levels of type I IFNs and IL-6.

体内活性: C-176 strongly reduces STING-mediated, but not RIG-I- or TBK1-mediated, IFNβ reporter activity. Pretreatment with C-176 markedly reduce the CMA-mediated induction of serum levels of type I IFNs and IL-6.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 60 mg/mL (167.56 mM)


关键字: STING | C 176 | Stimulator of Interferon Genes | inhibit | MPYS | ERIS | C-176 | TMEM173 | Inhibitor | MITA

相关产品: 2',3'-cGAMP | C-178 | SR-717 | STING-IN-2 | STING agonist-4 | MSA-2 | Cyclic-di-GMP disodium | ADU-S100 ammonium salt | Antitumor agent-114 | diABZI STING agonist-1 trihydrochloride

相关库: Immuno-Oncology Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Nonsteroidal Anti-Inflammatory Compound Library | NO PAINS Compound Library | Covalent Inhibitor Library | Bioactive Compound Library