Product Introduction
Bioactivity


英文名: Faltan

描述: Faltan (Folpet) 是一种广泛使用的二甲酰亚胺类杀菌剂，可诱发小鼠胃肠道肿瘤，主要发生在十二指肠，对人支气管上皮细胞也有细胞毒作用。

细胞实验: Sub-confluent 16HBE14o- plated on collagen-coated 60 mm dishes were exposed to Folpan 80WG particles corresponding to 0, 1.85 and 3.70 g/cm^2 folpet (0, 10 and 20 μM) for 2, 4 and 24 h in RPMI-1640 medium w/o phenol red , w/o FCS, supplemented with 1% l-glutamine (200 mM), 1% penicillin (10^4 U/ml), 1% streptomycin (10 mg/ml) and 1% fungizone (25 μg/ml)[1].

体外活性: Folpan 80WG particles result in a rapid cytotoxic effect on human bronchial epithelial cells in vitro that could be in part explained by oxidative stress, characterised by membrane lipid peroxidation and ROS production[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 125 mg/mL (421.50 mM)


关键字: Faltan | Fungal | Inhibitor | inhibit

相关产品: Kresoxim-Methyl | 3-(Methylthio)propionic acid | CONIFERYL ALCOHOL | Miconazole | 1-Dodecylimidazole | Fosfluconazole | Caerulomycin A | Kasugamycin hydrochloride | Pneumocandin B0 | Filastatin

相关库: Antibiotics Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Anti-Cancer Active Compound Library | Anti-Fungal Compound Library | NO PAINS Compound Library | Anti-Infection Compound Library | Bioactive Compound Library