Product IntroductionBioactivity英文名:
Protizinic acid描述: Protizinic acid 抑制磷脂酶 A2 (PLA2),IC50值为 210 μM。Protizinic acid 是具有抗炎和解热活性的,口服非甾体抗炎剂。
体外活性: Protizinic acid not only inhibits the in vitro generation of leukokinin but also antagonizes to it on the receptor site of leukokinin [1].
体内活性: In vivo leukokinin (LK) generation system using feline acute ischemia model, When 3 mg/kg Protizinic acid is injected twice intravenously to cats with acute cardiac ischemia, increased blood acid protease activity is inhibited and significant inhibitory action on the decrease of leukokininogen, the precursor of leukokinin, is observed [1]. Oral administration of 30 mg/kg of Protizinic acid significantly inhibits arachidonic acid-induced erythema in guinea pigs [2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year