Product IntroductionBioactivity英文名:
CDK1/Cyc B-IN-1描述: CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex, demonstrating selectivity with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, effectively halting cancer cell proliferation. Additionally, CDK1/Cyc B-IN-1 exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1].
体外活性: CDK1/Cyc B-IN-1 (Compound 5) shows cytotoxic activity with IC 50 values of 5.33 ± 0.69 μM and 21.69 ± 1.04 μM against HCT-116 and WI-38, respectively [1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year