化合物 PARP-1/HDAC-IN-1 T61962
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Product IntroductionBioactivity英文名: PARP-1/HDAC-IN-1描述: PARP-1/HDAC-IN-1 是有效的 PARP-1/HDAC6双重抑制剂，IC50分别为 68.90 nM 和 510 nM
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Product Introduction
Bioactivity
英文名: PARP-1/HDAC-IN-1
描述: PARP-1/HDAC-IN-1 是有效的 PARP-1/HDAC6双重抑制剂，IC50分别为 68.90 nM 和 510 nM。PARP-1/HDAC-IN-1 具有抗癌、抗迁移和抗血管生成活性。
体外活性: PARP-1/HDAC-IN-1 (Compound 1–8-6) possesses potent inhibitory activity against MDA-MB-436, ES-2, DU145, A549, HCC1937, and Capan-1 cells with IC 50 values of 0.35 μM, 1.16 μM, 3.38 μM, 5.67 μM, 2.85 μM, and 4.53 μM, respectively [1]. PARP-1/HDAC-IN-1 (Compound 1–8-6; 0.3-10 μM) is able to heighten expression level of acetylated α-tubulin with marginal effects to acetylated histones H3 and H4 [1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bioactivity
英文名: PARP-1/HDAC-IN-1
描述: PARP-1/HDAC-IN-1 是有效的 PARP-1/HDAC6双重抑制剂，IC50分别为 68.90 nM 和 510 nM。PARP-1/HDAC-IN-1 具有抗癌、抗迁移和抗血管生成活性。
体外活性: PARP-1/HDAC-IN-1 (Compound 1–8-6) possesses potent inhibitory activity against MDA-MB-436, ES-2, DU145, A549, HCC1937, and Capan-1 cells with IC 50 values of 0.35 μM, 1.16 μM, 3.38 μM, 5.67 μM, 2.85 μM, and 4.53 μM, respectively [1]. PARP-1/HDAC-IN-1 (Compound 1–8-6; 0.3-10 μM) is able to heighten expression level of acetylated α-tubulin with marginal effects to acetylated histones H3 and H4 [1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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