化合物AChE/BChE-IN-10 T61969
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Product IntroductionBioactivity英文名: AChE/BChE-IN-10描述: AChE/BChE-IN-10 (Compound 7b) 是有效的、血脑屏障渗透性的 AChE 和 BChE 双重抑制剂，IC50
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Product Introduction
Bioactivity
英文名: AChE/BChE-IN-10
描述: AChE/BChE-IN-10 (Compound 7b) 是有效的、血脑屏障渗透性的 AChE 和 BChE 双重抑制剂，IC50 值分别为 0.176 和 0.47 μM。AChE/BChE-IN-10 可以抑制 Aβ 的聚集。
体外活性: AChE/BChE-IN-10 inhibits AChE in a non-competitive manner (Ki= 0.21 μM), and BChE in a mixed-fashion(Ki= 0.15 μM)[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 4.03 mg/mL (10 mM)
相关产品: α-Conotoxin MII | Ethoxysanguinarine | Catharanthine | Atractyloside A | MHP 133 | Nitrobenzylthioinosine | Tosedostat | SCH-900271 | CDD0102 | Solifenacin succinate
相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Inhibitor Library | Bioactive Compound Library
Bioactivity
英文名: AChE/BChE-IN-10
描述: AChE/BChE-IN-10 (Compound 7b) 是有效的、血脑屏障渗透性的 AChE 和 BChE 双重抑制剂，IC50 值分别为 0.176 和 0.47 μM。AChE/BChE-IN-10 可以抑制 Aβ 的聚集。
体外活性: AChE/BChE-IN-10 inhibits AChE in a non-competitive manner (Ki= 0.21 μM), and BChE in a mixed-fashion(Ki= 0.15 μM)[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 4.03 mg/mL (10 mM)
相关产品: α-Conotoxin MII | Ethoxysanguinarine | Catharanthine | Atractyloside A | MHP 133 | Nitrobenzylthioinosine | Tosedostat | SCH-900271 | CDD0102 | Solifenacin succinate
相关库: Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Inhibitor Library | Bioactive Compound Library
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