Product Introduction
Bioactivity


英文名: Compound TPX-0046

描述: Compound TPX-0046 是有效的RET 的抑制剂。化合物TPX-046可以抑制RET 的自磷酸化。

体外活性: Compound TPX-0046 (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells[1].

体内活性: Compound TPX-0046 (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : Slightly soluble


关键字: Compound TPX-0046 | CompoundTPX0046 | Compound TPX 0046 | Compound TPX0046

相关产品: DUN73423 | AD80 | BT-13 | Agerafenib hydrochloride | Regorafenib | TPX-0046 | Amuvatinib | trans-Pralsetinib | Vepafestinib | Treprostinil Sodium

相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Bioactive Compound Library