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Product IntroductionBioactivity英文名: Arecoline描述: Arecoline 是一种来自棕榈科植物槟榔的天然生物碱，是有效的烟碱和毒蕈碱乙酰胆碱受体的部分激动剂。Arecoline 具有抗焦虑和抗寄生虫
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Product Introduction
Bioactivity
英文名: Arecoline
描述: Arecoline 是一种来自棕榈科植物槟榔的天然生物碱，是有效的烟碱和毒蕈碱乙酰胆碱受体的部分激动剂。Arecoline 具有抗焦虑和抗寄生虫活性，可诱导氧化应激，可用于研究阿尔茨海默病和老年性痴呆。
体外活性: Arecoline induces the generation of reactive oxygen species and cell cycle arrest at the G1/G0 phase in HaCaT cells without affecting the expression of p21/Cip1. Upregulation of the expression of stress-responsive genes, including hemeoxygenase-1, ferritin light chain, glucose-6-phosphate dehydrogenase, glutamatecysteine ligase catalytic subunit, and glutathione reductase, is observed in response to arecoline. Notably, arecoline-induced epithelial cell death at higher concentrations is attributed to oxidative trauma without eliciting apoptosis[1].
存储条件: keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 55 mg/mL (354.4 mM)
相关产品: Trolox | AKBA | CPS-11 | Argininosuccinic acid disodium | Methylprednisolone Acetate | Anti-inflammatory agent 47 | Isodeoxyelephantopin | 3-Indolepropionic acid | Ethyl 3,4-dihydroxybenzoate | Methyl Vanillate
相关库: Membrane Protein-targeted Compound Library | Anti-Parasitic Compound Library | Antiparasitic Natural Product Library
Bioactivity
英文名: Arecoline
描述: Arecoline 是一种来自棕榈科植物槟榔的天然生物碱，是有效的烟碱和毒蕈碱乙酰胆碱受体的部分激动剂。Arecoline 具有抗焦虑和抗寄生虫活性，可诱导氧化应激，可用于研究阿尔茨海默病和老年性痴呆。
体外活性: Arecoline induces the generation of reactive oxygen species and cell cycle arrest at the G1/G0 phase in HaCaT cells without affecting the expression of p21/Cip1. Upregulation of the expression of stress-responsive genes, including hemeoxygenase-1, ferritin light chain, glucose-6-phosphate dehydrogenase, glutamatecysteine ligase catalytic subunit, and glutathione reductase, is observed in response to arecoline. Notably, arecoline-induced epithelial cell death at higher concentrations is attributed to oxidative trauma without eliciting apoptosis[1].
存储条件: keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 55 mg/mL (354.4 mM)
相关产品: Trolox | AKBA | CPS-11 | Argininosuccinic acid disodium | Methylprednisolone Acetate | Anti-inflammatory agent 47 | Isodeoxyelephantopin | 3-Indolepropionic acid | Ethyl 3,4-dihydroxybenzoate | Methyl Vanillate
相关库: Membrane Protein-targeted Compound Library | Anti-Parasitic Compound Library | Antiparasitic Natural Product Library
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