化合物 AEG40730 HCl T70096
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Product IntroductionBioactivity英文名: AEG40730 HCl描述: AEG40730 is a potent and selective IAP antagonist and a BIR-binding t
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Product Introduction
Bioactivity
英文名: AEG40730 HCl
描述: AEG40730 is a potent and selective IAP antagonist and a BIR-binding tetrapeptide. AEG40730 binds to cIAP1 and cIAP2, facilitates their autoubiquitination and proteosomal degradation, and causes a dramatic reduction in RIP1 ubiquitination. Treatment with nanomolar concentrations of AEG40730 resulted in the loss of both XIAP and c-IAP1 proteins, albeit with different kinetics.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: AEG40730 HCl | Minophylline | Dynaphylline | Etophylate
Bioactivity
英文名: AEG40730 HCl
描述: AEG40730 is a potent and selective IAP antagonist and a BIR-binding tetrapeptide. AEG40730 binds to cIAP1 and cIAP2, facilitates their autoubiquitination and proteosomal degradation, and causes a dramatic reduction in RIP1 ubiquitination. Treatment with nanomolar concentrations of AEG40730 resulted in the loss of both XIAP and c-IAP1 proteins, albeit with different kinetics.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: AEG40730 HCl | Minophylline | Dynaphylline | Etophylate
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