Product Introduction
Bioactivity


英文名: 2-Chloroadenosine

描述: 2-Chloroadenosine 是腺苷类似物，可防止大鼠海马缺血细胞长期丢失。它是尿苷内流 (Ki:33 μM) 的竞争性抑制剂，高亲和力与硝基苄基硫肌苷结合 (Ki:0.18 mM)。它是一种人红细胞核苷转运体的转运渗透剂。

体内活性: 2-Chloroadenosine(CADO) has been used to activate adenosine receptors in the thalamus, generating anticonvulsive activity in a rat model of generalized seizures.?It has also been used to induce bronchoconstrictor effects in a guinea pig model of asthma and to study cardiovascular responses in normotensive and hypertensive rats

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 45 mg/mL (149.16 mM)


关键字: permeant | Inhibitor | influx,nitrobenzylthioinosine | inhibit | cell | human | 2 Chloroadenosine | transported | analogue | loss | 2-Chloroadenosine | 2Chloroadenosine | ischaemic | erythrocytes,uridine

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