Product Introduction
Bioactivity


英文名: Emicizumab

描述: Emicizumab(ACE 910) 是一种人源化单克隆抗体，桥接活化因子 IX 和激活因子 X，以模拟活化因子 VIII 的功能。Emicizumab 可用于预防和治疗血友病 A 。

体内活性: Emicizumab (1.5-10 mg/kg; i.v.; 24 hours before tail-clip bleeding) partially corrects blood loss in a hemophilia type A bleeding model with an FVIII equivalent of 9 U/dL.[1]Emicizumab (3 mg/kg; intravenously) provides additional hemostatic activity when combined with low-dose FVIII (10 U/dL).[1]

存储条件: store at low temperaturestore at -20°C

关键字: Emicizumab | ACE-910 | RO-5534262 | ACE910 | RO5534262