Product IntroductionBioactivity英文名:
Prezalumab描述: Prezalumab (AMG 557) 是一种针对 ICOSL 和 BAFF 的人源 IgG2 单克隆抗体。Prezalumab 可用于研究干燥综合征皮肤红斑狼疮、银屑病、系统性红斑狼疮关节炎和系统性红斑狼疮 (SLE)。
体内活性: In mouse NZB/NZW lupus model and collagen-induced arthritis (CIA) models, Prezalumab demonstrates more efficacious effects than a single ICOSL or BAFF inhibitor[1].Prezalumab, similar to the pharmacological effect of BAFF inhibition, reduces B cells in cynomolgus monkeys[1].
存储条件: store at low temperaturestore at -80°C
关键字:
AMG-557 |
AMG557 |
Prezalumab