Product Introduction
Bioactivity


英文名: Murlentamab

描述: Murlentamab (GM102) 是一种人源化抗 AMHRII 抗体。Murlentama 具有潜在的抗肿瘤活性，可诱导巨噬细胞介导的抗体依赖的细胞介导的细胞毒性作用 (ADCC)。Murl可通过募，集、活化T细胞激发促炎和抗肿瘤内环境。Murlentama 通过促进幼稚的巨噬细胞定向，促进肿瘤相关巨噬细胞 (TAM) 重编程来发挥抗肿瘤活性。

体内活性: In vivo, Murlentamab (20 mg/kg; intravenous injection; twice a week; for 4 weeks) inhibits tumor growth in a mouse liver cancer patient-derived xenograft (PDX) model[2].

存储条件: store at low temperaturestore at -80°C

关键字: GM-102 | Murlentamab | GM 102