化合物WDR5-IN-6 T77495
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Product IntroductionBioactivity英文名: WDR5-IN-6描述: WDR5-IN-6 是一种 WDR5 抑制剂，靶向 WBM 位点。WDR5-IN-6 与靶向 WIN 位点的 WDR5 抑制剂 OICR-942
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Product Introduction
Bioactivity
英文名: WDR5-IN-6
描述: WDR5-IN-6 是一种 WDR5 抑制剂，靶向 WBM 位点。WDR5-IN-6 与靶向 WIN 位点的 WDR5 抑制剂 OICR-9429 具有高度协同作用。WDR5-IN-6 具有较强的抗肿瘤活性，可抑制神经母细胞瘤细胞系的细胞增殖。WDR5-IN-6 可用于神经母细胞瘤的研究。
体外活性: WDR5-IN-6 (compound 19) inhibits the proliferation of IMR32 and LAN5 cells with EC50 values of 12.34 and 14.89 μM, respectively, has a moderate inhibitory effect on SK-N-AS cells, and has no effect on HEK293T cells at 20 μM.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (152.82 mM)
关键字: WDR5IN6 | WDR5-IN-6
相关产品: JAK-IN-26 | PP2 | JAK-IN-21 | AT9283 | ABBV-712 | Solcitinib | NVP-BSK805 2HCl (1092499-93-8(free base)) | GS-829845 | Linderalactone | Momelotinib Mesylate
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | Inhibitor Library | Anti-Cancer Active Compound Library | Bioactive Compound Library
Bioactivity
英文名: WDR5-IN-6
描述: WDR5-IN-6 是一种 WDR5 抑制剂，靶向 WBM 位点。WDR5-IN-6 与靶向 WIN 位点的 WDR5 抑制剂 OICR-9429 具有高度协同作用。WDR5-IN-6 具有较强的抗肿瘤活性，可抑制神经母细胞瘤细胞系的细胞增殖。WDR5-IN-6 可用于神经母细胞瘤的研究。
体外活性: WDR5-IN-6 (compound 19) inhibits the proliferation of IMR32 and LAN5 cells with EC50 values of 12.34 and 14.89 μM, respectively, has a moderate inhibitory effect on SK-N-AS cells, and has no effect on HEK293T cells at 20 μM.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (152.82 mM)
关键字: WDR5IN6 | WDR5-IN-6
相关产品: JAK-IN-26 | PP2 | JAK-IN-21 | AT9283 | ABBV-712 | Solcitinib | NVP-BSK805 2HCl (1092499-93-8(free base)) | GS-829845 | Linderalactone | Momelotinib Mesylate
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | Inhibitor Library | Anti-Cancer Active Compound Library | Bioactive Compound Library
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