N-(4-甲氧苯基)-1-苯基-1H-吡唑-3-胺 T8356
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Product IntroductionBioactivity英文名: FPL 62064描述: FPL 62064 是 5-脂氧合酶和COX 双重抑制剂，具有抗炎活性，对 RBL-1 胞质 5-脂氧合酶和前列腺素合成酶 (环氧化酶) 的IC
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Product Introduction
Bioactivity
英文名: FPL 62064
描述: FPL 62064 是 5-脂氧合酶和COX 双重抑制剂，具有抗炎活性，对 RBL-1 胞质 5-脂氧合酶和前列腺素合成酶 (环氧化酶) 的IC50值分别为 3.5 和 3.1 μM。
动物实验: Animal Model:Female LACA mice (20-30 g) injected with immune complex. Dosage:5 mg/kg, 10 mg/kg, 20 mg/kg. Administration:Intraperitoneal injection.
体内活性: FPL 62064 抑制了紫外线辐射引起的豚鼠红斑和 PGE2 形成，同时也抑制了由花生四烯酸在小鼠耳朵中产生的水肿和前列腺素产生。在兔子皮肤中与花生四烯酸共同注射时，FPL 62064 也有效抑制了水肿和前列腺素的形成。
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 250 mg/mL (942.29 mM)
关键字: Cyclooxygenase | LOX | 5-lipoxygenase | inhibit | Prostaglandin | 5-LOX | FPL62064 | COX | Inhibitor | FPL 62064 | synthetase | Lipoxygenase | anti-inflammatory | COX-2 | FPL-62064
相关产品: Lycopodine | ER-34122 | Caffeic Acid | Chebulagic acid | PF-4191834 | DKI5 | CJ-13,610 hydrochloride | CJ-13,610 | U-73122 | Cirsiliol
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | Neuronal Signaling Compound Library | Ferroptosis Compound Library | Inhibitor Library | Anti-Obesity Compound Library | Lipid Metabolism Compound Library | NO PAINS Compound Library | Bioactive Compound Library
Bioactivity
英文名: FPL 62064
描述: FPL 62064 是 5-脂氧合酶和COX 双重抑制剂，具有抗炎活性，对 RBL-1 胞质 5-脂氧合酶和前列腺素合成酶 (环氧化酶) 的IC50值分别为 3.5 和 3.1 μM。
动物实验: Animal Model:Female LACA mice (20-30 g) injected with immune complex. Dosage:5 mg/kg, 10 mg/kg, 20 mg/kg. Administration:Intraperitoneal injection.
体内活性: FPL 62064 抑制了紫外线辐射引起的豚鼠红斑和 PGE2 形成，同时也抑制了由花生四烯酸在小鼠耳朵中产生的水肿和前列腺素产生。在兔子皮肤中与花生四烯酸共同注射时，FPL 62064 也有效抑制了水肿和前列腺素的形成。
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 250 mg/mL (942.29 mM)
关键字: Cyclooxygenase | LOX | 5-lipoxygenase | inhibit | Prostaglandin | 5-LOX | FPL62064 | COX | Inhibitor | FPL 62064 | synthetase | Lipoxygenase | anti-inflammatory | COX-2 | FPL-62064
相关产品: Lycopodine | ER-34122 | Caffeic Acid | Chebulagic acid | PF-4191834 | DKI5 | CJ-13,610 hydrochloride | CJ-13,610 | U-73122 | Cirsiliol
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | Neuronal Signaling Compound Library | Ferroptosis Compound Library | Inhibitor Library | Anti-Obesity Compound Library | Lipid Metabolism Compound Library | NO PAINS Compound Library | Bioactive Compound Library
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