Product Introduction
Bioactivity


英文名: GKT136901

描述: GKT136901 (AK120765) 是选择性的和具有口服活性的 NADPH 氧化酶 NOX-1/4抑制剂，Ki 分别为 160 和 165 nM。它具有抗炎症活性。它也是一种选择性和直接的过氧亚硝酸清除剂。它可用于糖尿病肾病，中风和神经退行性疾病的研究。

体内活性: GKT136901是一种新型NOX-1/4抑制剂，可能在糖尿病肾病、中风或神经退行性疾病等领域有潜在应用[1]。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 32.5 mg/mL (88.6 mM)


关键字: peroxynitrite | scavenger | AK 120765 | neurodegeneration | GKT-136901 | NOX1/4 | NADPH | oxidase | inhibit | NOX | GKT136901 | NADPH Oxidase | AK-120765 | nephropathy | anti-inflammatory | GKT 136901 | stroke | Inhibitor | diabetic

相关产品: Phox-I2 | Pisatin | ML-090 | NoxA1ds acetate(1435893-78-9 free base) | (R)-Reticuline | 5'-Demethylaquillochin | NecroX-7 | Sprengerinin C | 5-Heneicosylresorcinol | gp91ds-tat

相关库: Mitochondria-Targeted Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Lipid Metabolism Compound Library | Anti-Fibrosis Compound Library | Metabolism Compound Library | Orally Active Compound Library | Preclinical Compound Library | Anti-Cardiovascular Disease Compound Library | Bioactive Compound Library