Product Introduction
Bioactivity


英文名: LYN-1604 dihydrochloride

描述: LYN-1604 2HCl 是一种有效的 UNC-51 样激酶 1 激活剂，EC50值为 18.94 nM。LYN-1604 可研究三阴性乳腺癌。

体外活性: LYN-1604, to be the best candidate for a ULK1 agonist.?LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604 has potential for good therapeutic effects on TNBC by targeting ULK1-modulated cell death in vivo

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 25 mg/mL (38.02 mM)


关键字: anti-tumor | Unc-51 like kinase | negative | cancer | Autophagy | LYN-1604 2HCl | breast | ULK1 | LYN1604 Dihydrochloride | ULK | 2216753-86-3 free base | LYN 1604 Dihydrochloride | Inhibitor | LYN1604 | 2216753-86-3 | LYN1604 dihydrochloride | LYN 1604 dihydrochloride | activator | TNBC | LYN-1604 | triple | LYN-1604 Dihydrochloride | LYN 1604 | inhibit | Apoptosis

相关产品: (R)-Isomucronulatol | MMRi64 | Deguelin | Tubulin inhibitor 32 | Lacidipine | Bioymifi | Betulinic acid | INH6 | Parthenolide | RSH-7

相关库: Anti-Breast Cancer Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Kinase Inhibitor Library | Anti-Cancer Active Compound Library | Apoptosis Compound Library | Autophagy Compound Library | NO PAINS Compound Library | Bioactive Compound Library